Direct synthesis of anilines and nitrosobenzenes from phenols.
نویسندگان
چکیده
A one-pot synthesis of anilines and nitrosobenzenes from phenols has been developed using an ipso-oxidative aromatic substitution ((i)SOAr) process. The products are obtained in good yields under mild and metal-free conditions. The leaving group effect on reactions that proceed through mixed quionone monoketals has also been investigated and a predictive model has been established.
منابع مشابه
Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc00941c
Phenols, being readily available from naturally abundant lignins, are important future feedstocks for the renewable production of fuels, chemicals, and energy. Herein, a highly efficient Pd-catalyzed direct coupling of phenolic lignin model monomers and analogues with anilines to give cyclohexylamines using cheap and safe sodium formate as hydrogen donor is described. A variety of secondary and...
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 14 24 شماره
صفحات -
تاریخ انتشار 2016